mskcc.oncotree - Interface to the 'OncoTree' API

Programmatic access to 'OncoTree' API <http://oncotree.mskcc.org/>. Get access to tumor main types, identifiers and utility routines to map across to other tumor classification systems.

Last updated 2 years ago

3.48 score 6 stars 7 scripts 191 downloads

quincunx - REST API Client for the 'PGS' Catalog

Programmatic access to the 'PGS' Catalog. This package provides easy access to 'PGS' Catalog data by accessing the REST API <https://www.pgscatalog.org/rest/>.

Last updated 2 years ago

ebigwaspolygenic-risk-scorespolygenic-scores

3.10 score 14 stars 18 scripts 213 downloads

agvgd - An R Implementation of the 'Align-GVGD' Method

'Align-GVGD' ('A-GVGD') is a method to predict the impact of 'missense' substitutions based on the properties of amino acid side chains and protein multiple sequence alignments <doi:10.1136/jmg.2005.033878>. 'A-GVGD' is an extension of the original 'Grantham' distance to multiple sequence alignments. This package provides an alternative R implementation to the web version found on <http://agvgd.hci.utah.edu/>.

Last updated 11 months ago

3.00 score 2 stars 7 scripts 296 downloads

grantham - Calculate the 'Grantham' Distance

A minimal set of routines to calculate the 'Grantham' distance <doi:10.1126/science.185.4154.862>. The 'Grantham' distance attempts to provide a proxy for the evolutionary distance between two amino acids based on three key chemical properties: composition, polarity and molecular volume. In turn, evolutionary distance is used as a proxy for the impact of missense mutations. The higher the distance, the more deleterious the substitution is expected to be.

Last updated 4 months ago

2.78 score 4 stars 1 packages 7 scripts 234 downloads