quincunx - REST API Client for the 'PGS' Catalog
Programmatic access to the 'PGS' Catalog. This package provides easy access to 'PGS' Catalog data by accessing the REST API <https://www.pgscatalog.org/rest/>.
Last updated 2 years ago
ebigwaspolygenic-risk-scorespolygenic-scores
14 stars 1.45 score 48 dependenciesmskcc.oncotree - Interface to the 'OncoTree' API
Programmatic access to 'OncoTree' API <http://oncotree.mskcc.org/>. Get access to tumor main types, identifiers and utility routines to map across to other tumor classification systems.
Last updated 2 years ago
6 stars 1.18 score 43 dependenciesagvgd - An R Implementation of the 'Align-GVGD' Method
'Align-GVGD' ('A-GVGD') is a method to predict the impact of 'missense' substitutions based on the properties of amino acid side chains and protein multiple sequence alignments <doi:10.1136/jmg.2005.033878>. 'A-GVGD' is an extension of the original 'Grantham' distance to multiple sequence alignments. This package provides an alternative R implementation to the web version found on <http://agvgd.hci.utah.edu/>.
Last updated 9 months ago
2 stars 1.03 score 33 dependenciesgrantham - Calculate the 'Grantham' Distance
A minimal set of routines to calculate the 'Grantham' distance <doi:10.1126/science.185.4154.862>. The 'Grantham' distance attempts to provide a proxy for the evolutionary distance between two amino acids based on three key chemical properties: composition, polarity and molecular volume. In turn, evolutionary distance is used as a proxy for the impact of missense mutations. The higher the distance, the more deleterious the substitution is expected to be.
Last updated 2 months ago
4 stars 1.00 score 21 dependencies 1 dependents